ChemicalBook > CAS DataBase List > Hh-Ag 1.3
Hh-Ag 1.3
- Product Name
- Hh-Ag 1.3
- CAS No.
- 364590-63-6
- Chemical Name
- Hh-Ag 1.3
- Synonyms
- Hh-Ag 1.3;Smoothened Agonist, HCl;Frizzled6 agonist SAG1.3;SAG . dihydrochloride (water soluble);3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
- CBNumber
- CB72524538
- Molecular Formula
- C28H28ClN3OS
- Formula Weight
- 490.06
- MOL File
- 364590-63-6.mol
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Hh-Ag 1.3 Property
- Boiling point:
- 688.6±55.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- pka
- 10?+-.0.40(Predicted)
- form
- White to off-white solid.
- Water Solubility
- Soluble in water.
- Sensitive
- Light Sensitive & Hygroscopic
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 566660
- Product name
- Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
- Packaging
- 1mg
- Price
- $361
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 566660
- Product name
- Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
- Packaging
- 5mg
- Price
- $1030
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- J64726
- Product name
- Smoothened Agonist dihydrochloride dihydrate
- Packaging
- 1mg
- Price
- $117
- Updated
- 2021/12/16
Alfa Aesar
- Product number
- J64726
- Product name
- Smoothened Agonist dihydrochloride dihydrate
- Packaging
- 5mg
- Price
- $415
- Updated
- 2021/12/16
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Hh-Ag 1.3 Chemical Properties,Usage,Production
Uses
Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.
Hh-Ag 1.3 Preparation Products And Raw materials
Raw materials
Preparation Products
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Hh-Ag 1.3 Suppliers
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52927
- Advantage
- 58
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